Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 100.0 61
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 131.0 53
RA1869 TNF-a 100
ng/mL
 1
IL-1RA
 138.0 59
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 142.0 51
N2759 TNF-a 100
ng/mL
 1
IL-1RA
 145.0 43
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 137.0 45
RA1931 TNF-a 100
ng/mL
 1
IL-1RA
 137.0 51
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-1RA
 130.0 47
N2586 TNF-a 100
ng/mL
 1
IL-1RA
 141.0 50
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 21.0 50
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 25.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 21.5 62
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 36.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 26.0 55
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 29.0 39
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 26.0 45
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 41.0 49
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 78.0 35
RA1869 IL-1 alpha 100
ng/mL
 1
IL-1RA
 84.0 54
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 108.0 38
N2759 IL-1 alpha 100
ng/mL
 1
IL-1RA
 86.0 47
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 79.0 41
RA1931 IL-1 alpha 100
ng/mL
 1
IL-1RA
 81.0 47
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-1RA
 93.0 47
N2586 IL-1 alpha 100
ng/mL
 1
IL-1RA
 90.0 55