Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 38.0 79
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 39.5 90
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 40.0 57
RA1869 IL-1 alpha 100
ng/mL
 3
IFN-a2
 25.0 78
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 38.0 66
N2759 IL-1 alpha 100
ng/mL
 3
IFN-a2
 38.0 81
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 40.0 62
RA1931 IL-1 alpha 100
ng/mL
 3
IFN-a2
 36.0 57
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IFN-a2
 42.0 65
N2586 IL-1 alpha 100
ng/mL
 3
IFN-a2
 40.0 64
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 20.0 75
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 19.0 71
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 20.0 78
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 23.0 63
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 20.5 80
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 22.0 69
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 19.0 84
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 23.0 79
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 21.0 85
RA1869 TNF-a 100
ng/mL
 3
IFN-a2
 23.0 59
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 24.0 74
N2759 TNF-a 100
ng/mL
 3
IFN-a2
 24.0 61
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 22.0 69
RA1931 TNF-a 100
ng/mL
 3
IFN-a2
 21.0 63
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IFN-a2
 23.0 70