Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MIG
 106.0 74
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 24.0 69
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MIG
 35.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 23.5 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MIG
 96.0 73
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MIG
 33.0 61
RA1869 TNF-a 100
ng/mL
 3
MIG
 33.0 56
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MIG
 233.0 55
N2759 TNF-a 100
ng/mL
 3
MIG
 237.0 53
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MIG
 48.0 48
RA1931 TNF-a 100
ng/mL
 3
MIG
 53.0 48
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MIG
 137.5 66
N2586 TNF-a 100
ng/mL
 3
MIG
 158.0 50
RA1869 5z-7-oxozeaenol 0.6
uM
 3
MIG
 17.0 67
RA1869 IKK16 2.0
uM
 3
MIG
 16.0 81
N2759 5z-7-oxozeaenol 0.6
uM
 3
MIG
 51.0 67
N2759 IKK16 2.0
uM
 3
MIG
 50.0 71
RA1931 5z-7-oxozeaenol 0.6
uM
 3
MIG
 16.0 55
RA1931 IKK16 2.0
uM
 3
MIG
 16.5 66
N2586 5z-7-oxozeaenol 0.6
uM
 3
MIG
 24.0 63
N2586 IKK16 2.0
uM
 3
MIG
 21.0 63
RA1869 Tofacitinib 0.3
uM
 3
MIG
 14.0 62
RA1869 3
MIG
 11.0 63
N2759 Tofacitinib 0.3
uM
 3
MIG
 41.0 62
N2759 3
MIG
 47.5 48