Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Poly(I:C) 2
ug/mL
 4
IL-17
 112.5 64
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 83.0 55
N2645 Poly(I:C) 2
ug/mL
 4
IL-17
 124.0 47
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 114.0 43
RA2708 Poly(I:C) 2
ug/mL
 4
IL-17
 103.5 42
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 61.0 49
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 78.0 54
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 59.0 67
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 65.0 66
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 59.5 70
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 74.0 64
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 125.0 67
RA2159 IL-1 alpha 100
ng/mL
 4
IL-17
 124.5 64
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 98.0 53
N2645 IL-1 alpha 100
ng/mL
 4
IL-17
 106.0 30
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-17
 136.0 53
RA2708 IL-1 alpha 100
ng/mL
 4
IL-17
 125.0 70
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 150.0 65
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 134.0 68
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 116.0 74
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 123.0 64
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-17
 120.5 56
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-17
 128.0 57
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-17
 146.5 56
RA2159 TNF-a 100
ng/mL
 4
IL-17
 149.5 56