Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 TNF-a 100
ng/mL
 2
IL-12 (p70)
 88.0 45
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 74.5 54
N2645 TNF-a 100
ng/mL
 2
IL-12 (p70)
 79.0 69
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 70.0 70
RA2708 TNF-a 100
ng/mL
 2
IL-12 (p70)
 77.5 56
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 43.0 58
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 54.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 43.0 52
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 67.0 70
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 48.0 70
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 42.0 60
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 93.0 43
RA2159 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 69.0 56
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 65.0 64
N2645 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 95.5 58
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 109.5 52
RA2708 IL-1 alpha 100
ng/mL
 2
IL-12 (p70)
 85.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 43.0 55
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 50.0 71
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 32.0 62
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 48.0 74
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 44.0 67
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 41.0 71
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 56.0 66
RA2159 Poly(I:C) 2
ug/mL
 2
IL-12 (p70)
 59.5 50