Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 14.5 48
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 18.0 45
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 14.0 38
RA1869 IL-1 alpha 100
ng/mL
 1
IL-7
 32.0 25
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 28.5 30
N2759 IL-1 alpha 100
ng/mL
 1
IL-7
 23.5 30
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 20.5 44
RA1931 IL-1 alpha 100
ng/mL
 1
IL-7
 22.0 47
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-7
 22.5 42
N2586 IL-1 alpha 100
ng/mL
 1
IL-7
 22.0 43
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 12.0 76
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 15.0 74
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 26.0 71
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 24.5 70
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 18.5 68
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 25.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 13.0 61
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 16.0 59
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 12.0 54
RA1869 Poly(I:C) 2
ug/mL
 1
IL-7
 12.5 58
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 25.0 50
N2759 Poly(I:C) 2
ug/mL
 1
IL-7
 29.0 49
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 20.0 55
RA1931 Poly(I:C) 2
ug/mL
 1
IL-7
 19.0 39
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IL-7
 21.0 58