Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 18.0 72
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 25.0 62
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 19.0 49
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 32.0 55
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 74.0 57
RA1869 IL-1 alpha 100
ng/mL
 1
IFN-g
 80.0 59
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 95.0 51
N2759 IL-1 alpha 100
ng/mL
 1
IFN-g
 78.5 60
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 69.5 56
RA1931 IL-1 alpha 100
ng/mL
 1
IFN-g
 75.0 63
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IFN-g
 94.0 59
N2586 IL-1 alpha 100
ng/mL
 1
IFN-g
 87.5 56
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 16.0 63
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 15.0 71
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 14.5 72
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 17.0 74
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 20.0 88
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 21.0 68
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 17.0 77
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 19.0 66
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 24.5 50
RA1869 Poly(I:C) 2
ug/mL
 1
IFN-g
 40.0 64
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 46.0 55
N2759 Poly(I:C) 2
ug/mL
 1
IFN-g
 65.0 55
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
IFN-g
 52.0 65