Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 2
IL-10
 59.5 68
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 61.5 60
RA2708 TNF-a 100
ng/mL
 2
IL-10
 68.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 38.0 69
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 39.0 92
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 38.0 71
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 45.5 52
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 44.0 59
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 44.0 52
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 62.0 55
RA2159 IL-1 alpha 100
ng/mL
 2
IL-10
 56.0 61
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 57.0 51
N2645 IL-1 alpha 100
ng/mL
 2
IL-10
 57.5 58
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 59.0 60
RA2708 IL-1 alpha 100
ng/mL
 2
IL-10
 56.5 54
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 35.0 57
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 42.0 60
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 33.5 62
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 33.0 81
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 36.0 61
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 37.0 50
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 40.0 66
RA2159 Poly(I:C) 2
ug/mL
 2
IL-10
 54.0 59
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 43.0 53
N2645 Poly(I:C) 2
ug/mL
 2
IL-10
 48.0 51