Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 TNF-a 100
ng/mL
 1
IL-10
 70.0 37
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 80.0 47
RA1931 TNF-a 100
ng/mL
 1
IL-10
 58.0 61
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 75.0 47
N2586 TNF-a 100
ng/mL
 1
IL-10
 65.0 46
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 36.0 57
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 40.0 60
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 34.5 68
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 50.0 52
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 37.0 47
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 52.0 47
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 53.0 44
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 43.0 39
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 60.0 46
RA1869 IL-1 alpha 100
ng/mL
 1
IL-10
 71.5 46
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 70.0 40
N2759 IL-1 alpha 100
ng/mL
 1
IL-10
 53.0 55
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 62.5 48
RA1931 IL-1 alpha 100
ng/mL
 1
IL-10
 52.5 44
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-10
 69.0 42
N2586 IL-1 alpha 100
ng/mL
 1
IL-10
 61.0 51
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 30.0 57
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 45.0 58
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 42.0 69
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-10
 43.0 72