Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 105.0 53
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 114.0 69
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 90.0 56
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 95.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-4
 105.5 70
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-4
 105.0 63
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 117.0 67
RA2159 TNF-a 100
ng/mL
 4
IL-4
 136.0 69
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 106.0 49
N2645 TNF-a 100
ng/mL
 4
IL-4
 114.0 59
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-4
 110.0 59
RA2708 TNF-a 100
ng/mL
 4
IL-4
 104.0 43
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 26.5 56
RA2159 IKK16 2.0
uM
 4
IL-4
 26.0 51
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 23.5 56
N2645 IKK16 2.0
uM
 4
IL-4
 25.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-4
 23.0 59
RA2708 IKK16 2.0
uM
 4
IL-4
 24.0 52
RA2159 Tofacitinib 0.3
uM
 4
IL-4
 20.5 62
RA2159 4
IL-4
 27.0 67
N2645 Tofacitinib 0.3
uM
 4
IL-4
 20.0 39
N2645 4
IL-4
 22.0 73
RA2708 Tofacitinib 0.3
uM
 4
IL-4
 22.5 48
RA2708 4
IL-4
 21.0 62
RA2159 4
IL-4
 24.0 50