Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 19.0 57
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 25.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 19.0 74
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 23.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 19.5 62
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 20.0 70
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 25.0 57
RA2159 IL-1 alpha 100
ng/mL
 4
IL-13
 25.0 53
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 18.5 54
N2645 IL-1 alpha 100
ng/mL
 4
IL-13
 26.0 59
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-13
 28.5 58
RA2708 IL-1 alpha 100
ng/mL
 4
IL-13
 26.5 56
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 22.0 75
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 24.0 47
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 18.0 79
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 19.0 50
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-13
 23.0 61
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-13
 23.0 67
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 23.0 69
RA2159 TNF-a 100
ng/mL
 4
IL-13
 26.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 18.5 46
N2645 TNF-a 100
ng/mL
 4
IL-13
 21.0 64
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-13
 26.0 74
RA2708 TNF-a 100
ng/mL
 4
IL-13
 22.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-13
 23.0 64