Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 3025.0 | 77 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 1100.0 | 90 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 5496.0 | 71 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 4407.5 | 64 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 10179.0 | 73 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 2408.5 | 72 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 6293.0 | 57 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 15144.5 | 54 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 4909.0 | 55 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 26186.0 | 41 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 30550.0 | 57 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 4166.0 | 61 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 3857.0 | 40 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 37702.5 | 52 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-6 | 38376.5 | 64 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 1510.0 | 55 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | IL-6 | 1865.0 | 67 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 1088.0 | 75 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | IL-6 | 1496.5 | 74 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 3139.0 | 51 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | IL-6 | 4837.5 | 70 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-6 | 3741.0 | 47 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-6 | 1783.0 | 61 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | IL-6 | 1512.0 | 53 | ||||
| RA1869 | 1 | IL-6 | 58.5 | 52 |