Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 161.0 79
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 144.0 92
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 162.0 57
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 1611.5 76
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 298.0 66
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 179.5 54
RA2159 TNF-a 100
ng/mL
 2
FGF Basic
 184.0 65
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 153.5 48
N2645 TNF-a 100
ng/mL
 2
FGF Basic
 160.5 68
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
FGF Basic
 179.0 59
RA2708 TNF-a 100
ng/mL
 2
FGF Basic
 177.5 54
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 52.5 84
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 60.0 77
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 37.0 57
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 50.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 45.5 66
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 56.5 70
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 109.0 43
RA2159 IL-1 alpha 100
ng/mL
 2
FGF Basic
 94.0 65
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 69.5 60
N2645 IL-1 alpha 100
ng/mL
 2
FGF Basic
 82.5 84
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
FGF Basic
 113.0 55
RA2708 IL-1 alpha 100
ng/mL
 2
FGF Basic
 110.0 60
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
FGF Basic
 55.5 62
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
FGF Basic
 54.0 77