Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 40.0 | 53 | |
| RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 46.0 | 63 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 27.0 | 59 | |
| N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 50.0 | 53 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 47.0 | 53 | |
| RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 53.0 | 44 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 55.0 | 36 | |
| N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 62.5 | 38 | |
| RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 104.0 | 38 | |
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 101.0 | 50 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 106.0 | 34 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 77.0 | 54 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 87.0 | 45 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 85.0 | 57 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 111.5 | 48 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | Eotaxin | 95.0 | 50 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 33.5 | 58 | |
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 40.0 | 57 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 46.0 | 67 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 46.0 | 61 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 43.0 | 54 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 45.5 | 52 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 42.0 | 66 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 51.0 | 51 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | Eotaxin | 45.5 | 54 |