Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-1B
 18.0 94
N2645 IKK16 2.0
uM
 4
IL-1B
 19.0 68
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-1B
 16.0 86
RA2708 IKK16 2.0
uM
 4
IL-1B
 38.0 81
RA2159 Tofacitinib 0.3
uM
 4
IL-1B
 18.0 74
RA2159 4
IL-1B
 20.0 76
N2645 Tofacitinib 0.3
uM
 4
IL-1B
 19.0 71
N2645 4
IL-1B
 17.0 57
RA2708 Tofacitinib 0.3
uM
 4
IL-1B
 18.0 72
RA2708 4
IL-1B
 15.0 64
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 20.5 64
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 39.0 66
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 18.0 71
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 17.0 85
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 19.0 83
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 20.0 47
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 48.0 87
RA2159 Poly(I:C) 2
ug/mL
 4
IL-1B
 67.0 69
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 40.5 56
N2645 Poly(I:C) 2
ug/mL
 4
IL-1B
 82.5 60
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-1B
 82.5 66
RA2708 Poly(I:C) 2
ug/mL
 4
IL-1B
 57.0 58
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 22.0 63
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 33.0 71
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-1B
 28.0 81