Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 50.5 64
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 61.5 50
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 51.0 79
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 62.0 58
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 95.0 44
RA1869 IL-1 alpha 100
ng/mL
 3
IL-2
 87.0 59
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 97.5 50
N2759 IL-1 alpha 100
ng/mL
 3
IL-2
 96.5 56
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 93.0 64
RA1931 IL-1 alpha 100
ng/mL
 3
IL-2
 86.0 66
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-2
 87.5 52
N2586 IL-1 alpha 100
ng/mL
 3
IL-2
 100.5 64
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 95.0 60
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 104.0 80
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 72.0 73
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 92.5 52
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 92.5 60
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 95.0 64
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-2
 79.0 65
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-2
 104.0 72
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 115.5 56
RA1869 TNF-a 100
ng/mL
 3
IL-2
 112.0 52
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 107.5 58
N2759 TNF-a 100
ng/mL
 3
IL-2
 116.0 59
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-2
 117.0 53