Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-2
 49.5 50
N2645 IKK16 2.0
uM
 2
IL-2
 36.5 56
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-2
 55.5 52
RA2708 IKK16 2.0
uM
 2
IL-2
 51.0 53
RA2159 Tofacitinib 0.3
uM
 2
IL-2
 46.0 59
RA2159 2
IL-2
 54.5 62
N2645 Tofacitinib 0.3
uM
 2
IL-2
 50.0 50
N2645 2
IL-2
 54.0 55
RA2708 Tofacitinib 0.3
uM
 2
IL-2
 48.0 60
RA2708 2
IL-2
 50.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 97.0 64
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 107.0 59
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 105.5 66
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 107.0 47
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-2
 86.0 57
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-2
 107.0 47
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 124.0 49
RA2159 TNF-a 100
ng/mL
 2
IL-2
 123.5 60
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 96.0 53
N2645 TNF-a 100
ng/mL
 2
IL-2
 110.5 58
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-2
 112.0 53
RA2708 TNF-a 100
ng/mL
 2
IL-2
 126.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 54.0 48
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 59.0 78
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-2
 54.0 53