Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 27.0 60
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 29.5 70
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 59.5 58
RA2159 Poly(I:C) 2
ug/mL
 4
TNF-a
 76.0 60
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 46.0 59
N2645 Poly(I:C) 2
ug/mL
 4
TNF-a
 88.0 57
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TNF-a
 86.0 57
RA2708 Poly(I:C) 2
ug/mL
 4
TNF-a
 64.0 69
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 31.0 57
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 40.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 24.5 72
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 27.5 62
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 23.0 68
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 42.0 84
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 99.0 59
RA2159 IL-1 alpha 100
ng/mL
 4
TNF-a
 102.0 70
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 59.0 54
N2645 IL-1 alpha 100
ng/mL
 4
TNF-a
 76.0 61
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TNF-a
 100.0 51
RA2708 IL-1 alpha 100
ng/mL
 4
TNF-a
 104.0 67
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 26780.0 59
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNF-a
 25889.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 24839.0 54
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNF-a
 25958.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNF-a
 24908.0 51