Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 3
TNF-a
 22.0 71
RA1931 3
TNF-a
 22.0 62
N2586 Tofacitinib 0.3
uM
 3
TNF-a
 21.0 79
N2586 3
TNF-a
 20.5 82
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 21.0 85
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 20.0 65
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 20.0 85
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 21.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 21.5 70
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 22.0 80
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 19.0 62
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 27.0 91
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 48.5 68
RA1869 Poly(I:C) 2
ug/mL
 3
TNF-a
 53.0 72
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 66.5 66
N2759 Poly(I:C) 2
ug/mL
 3
TNF-a
 64.0 56
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 59.5 70
RA1931 Poly(I:C) 2
ug/mL
 3
TNF-a
 81.0 73
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNF-a
 83.0 60
N2586 Poly(I:C) 2
ug/mL
 3
TNF-a
 82.0 55
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 21.0 99
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 25.0 72
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 20.5 72
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 42.0 82
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNF-a
 19.5 86