Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 21.0 81
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 33.5 74
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 90.0 56
RA2159 IL-1 alpha 100
ng/mL
 2
TNF-a
 85.0 70
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 52.0 87
N2645 IL-1 alpha 100
ng/mL
 2
TNF-a
 65.0 64
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNF-a
 98.5 60
RA2708 IL-1 alpha 100
ng/mL
 2
TNF-a
 98.0 58
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 23.0 60
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 26.0 79
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 18.0 78
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 21.0 77
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 20.0 58
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 20.0 75
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 50.0 63
RA2159 Poly(I:C) 2
ug/mL
 2
TNF-a
 63.0 63
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 31.0 64
N2645 Poly(I:C) 2
ug/mL
 2
TNF-a
 64.0 61
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNF-a
 71.5 64
RA2708 Poly(I:C) 2
ug/mL
 2
TNF-a
 77.0 66
RA2159 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 23.0 59
RA2159 IKK16 2.0
uM
 2
TNF-a
 21.0 89
N2645 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 20.0 67
N2645 IKK16 2.0
uM
 2
TNF-a
 18.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 2
TNF-a
 21.0 47