Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 17.5 52
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 31.0 62
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 22.0 57
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 27.5 58
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 23.0 63
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 39.0 55
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 77.0 51
RA1869 IL-1 alpha 100
ng/mL
 1
TNF-a
 100.0 48
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 89.5 40
N2759 IL-1 alpha 100
ng/mL
 1
TNF-a
 90.0 47
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 78.5 46
RA1931 IL-1 alpha 100
ng/mL
 1
TNF-a
 83.5 70
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
TNF-a
 105.5 58
N2586 IL-1 alpha 100
ng/mL
 1
TNF-a
 98.5 50
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 19.0 63
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 17.5 66
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 22.0 81
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 23.0 67
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 21.0 70
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 26.5 64
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 24.0 65
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 25.0 63
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 30.5 54
RA1869 Poly(I:C) 2
ug/mL
 1
TNF-a
 55.5 60
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
TNF-a
 61.0 51