Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 361.5 76
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 434.5 74
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 475.0 66
RA2159 TNF-a 100
ng/mL
 2
GM-CSF
 466.5 52
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 422.0 52
N2645 TNF-a 100
ng/mL
 2
GM-CSF
 456.0 84
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
GM-CSF
 481.0 59
RA2708 TNF-a 100
ng/mL
 2
GM-CSF
 470.0 59
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 281.5 80
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 292.0 87
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 283.0 75
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 343.5 76
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 297.5 60
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 361.0 70
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 451.0 58
RA2159 IL-1 alpha 100
ng/mL
 2
GM-CSF
 411.0 81
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 397.5 74
N2645 IL-1 alpha 100
ng/mL
 2
GM-CSF
 403.0 60
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
GM-CSF
 448.5 52
RA2708 IL-1 alpha 100
ng/mL
 2
GM-CSF
 492.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 267.5 68
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 307.0 75
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 283.0 81
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 307.5 76
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
GM-CSF
 288.0 71