Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 337.5 64
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 340.0 59
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 433.0 65
RA1869 TNF-a 100
ng/mL
 1
GM-CSF
 437.0 83
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 342.0 53
N2759 TNF-a 100
ng/mL
 1
GM-CSF
 404.5 44
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 418.0 53
RA1931 TNF-a 100
ng/mL
 1
GM-CSF
 376.5 76
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 335.0 52
N2586 TNF-a 100
ng/mL
 1
GM-CSF
 398.5 58
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 222.0 67
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 227.0 68
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 236.5 48
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 240.5 70
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 224.5 54
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 252.0 38
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 231.0 68
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 282.0 47
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 366.0 53
RA1869 IL-1 alpha 100
ng/mL
 1
GM-CSF
 365.0 50
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 375.5 56
N2759 IL-1 alpha 100
ng/mL
 1
GM-CSF
 404.5 60
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 370.0 45
RA1931 IL-1 alpha 100
ng/mL
 1
GM-CSF
 355.5 60
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
GM-CSF
 356.0 59