Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 2
MMP-3
 49.0 49
RA2159 2
MMP-3
 48.0 57
N2645 Tofacitinib 0.3
uM
 2
MMP-3
 45.0 63
N2645 2
MMP-3
 33.0 60
RA2708 Tofacitinib 0.3
uM
 2
MMP-3
 126.0 51
RA2708 2
MMP-3
 80.5 30
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-3
 44.5 36
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-3
 64.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-3
 39.5 54
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-3
 42.5 54
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-3
 114.5 70
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-3
 595.5 50
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-3
 75.5 54
RA2159 TNF-a 100
ng/mL
 2
MMP-3
 123.5 54
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-3
 107.0 59
N2645 TNF-a 100
ng/mL
 2
MMP-3
 121.5 60
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-3
 6503.5 34
RA2708 TNF-a 100
ng/mL
 2
MMP-3
 4781.0 49
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 63.0 50
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 100.0 52
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 46.0 40
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 66.0 47
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 141.5 72
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 2210.0 61
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-3
 1903.5 44