Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 TNF-a 100
ng/mL
 2
MMP-2
 160.5 50
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 139.5 36
N2645 TNF-a 100
ng/mL
 2
MMP-2
 116.0 49
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 330.0 29
RA2708 TNF-a 100
ng/mL
 2
MMP-2
 541.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 147.0 54
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 186.5 44
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 105.0 43
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 99.5 34
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 282.5 50
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 423.0 29
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 153.0 31
RA2159 IL-1 alpha 100
ng/mL
 2
MMP-2
 150.0 50
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 116.0 43
N2645 IL-1 alpha 100
ng/mL
 2
MMP-2
 97.0 31
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MMP-2
 318.0 36
RA2708 IL-1 alpha 100
ng/mL
 2
MMP-2
 355.0 28
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 131.0 49
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 162.0 25
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 92.0 51
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 113.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 251.0 44
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 268.5 50
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
MMP-2
 145.0 45
RA2159 Poly(I:C) 2
ug/mL
 2
MMP-2
 116.0 36