Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 296.0 29
RA1869 IKK16 2.0
uM
 1
MMP-2
 530.0 35
N2759 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 227.0 35
N2759 IKK16 2.0
uM
 1
MMP-2
 351.5 46
RA1931 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 214.5 52
RA1931 IKK16 2.0
uM
 1
MMP-2
 115.0 55
N2586 5z-7-oxozeaenol 0.6
uM
 1
MMP-2
 552.0 34
N2586 IKK16 2.0
uM
 1
MMP-2
 422.0 46
RA1869 Tofacitinib 0.3
uM
 1
MMP-2
 339.0 36
RA1869 1
MMP-2
 560.0 27
N2759 Tofacitinib 0.3
uM
 1
MMP-2
 297.5 28
N2759 1
MMP-2
 506.5 30
RA1931 Tofacitinib 0.3
uM
 1
MMP-2
 160.5 46
RA1931 1
MMP-2
 310.0 27
N2586 Tofacitinib 0.3
uM
 1
MMP-2
 450.0 35
N2586 1
MMP-2
 363.0 33
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 389.0 50
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 483.5 28
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 369.0 50
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 519.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 211.0 42
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 146.5 54
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
MMP-2
 488.0 30
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
MMP-2
 721.5 28
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 308.0 30