Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 Poly(I:C) 2
ug/mL
4
MMP-2
94.0 46
N2645 IL-1 alpha 100
ng/mL
4
MMP-3
2146.5 54
RA2159 5z-7-oxozeaenol 0.6
uM
4
CTACK
17.0 46
N2645 4
CTACK
16.0 64
RA2708 5z-7-oxozeaenol 0.6
uM
4
CTACK
16.0 65
RA2708 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
4
CTACK
29.0 43
RA2708 5z-7-oxozeaenol 0.6
uM
4
MMP-3
129.0 63
N2645 4
CTACK
19.0 51
RA2708 TNF-a 100
ng/mL
4
MMP-3
7354.0 43
N2645 Tofacitinib 0.3
uM
4
MMP-3
40.0 51
RA2159 IL-1 alpha 100
ng/mL
4
MMP-2
112.0 39
RA2159 IKK16 2.0
uM
TNF-a 100
ng/mL
4
MMP-3
61.0 50
RA2159 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
4
MMP-2
140.0 50