Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
M-CSF
 374.0 41
N2586 Poly(I:C) 2
ug/mL
 3
M-CSF
 323.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 440.5 72
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 314.0 50
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 463.5 64
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 243.5 74
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 314.5 60
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 404.0 57
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 310.5 64
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 368.5 62
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 490.0 77
RA1869 IL-1 alpha 100
ng/mL
 3
M-CSF
 508.5 60
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 658.0 51
N2759 IL-1 alpha 100
ng/mL
 3
M-CSF
 648.0 53
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 597.0 43
RA1931 IL-1 alpha 100
ng/mL
 3
M-CSF
 460.0 38
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
M-CSF
 531.0 43
N2586 IL-1 alpha 100
ng/mL
 3
M-CSF
 393.0 40
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
M-CSF
 328.0 64
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
M-CSF
 312.0 52
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
M-CSF
 682.0 45
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
M-CSF
 660.0 53
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
M-CSF
 368.5 50
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
M-CSF
 393.5 48
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
M-CSF
 540.0 42