Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 2
M-CSF
 862.0 39
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
M-CSF
 792.0 50
RA2708 TNF-a 100
ng/mL
 2
M-CSF
 750.0 42
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 409.0 61
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 438.0 58
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 632.0 44
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 601.5 50
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 502.0 53
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 629.0 37
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 678.0 42
RA2159 IL-1 alpha 100
ng/mL
 2
M-CSF
 608.0 52
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 962.0 43
N2645 IL-1 alpha 100
ng/mL
 2
M-CSF
 858.0 41
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
M-CSF
 640.0 48
RA2708 IL-1 alpha 100
ng/mL
 2
M-CSF
 588.5 40
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 396.5 38
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 255.5 48
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 347.5 56
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 361.0 65
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 330.0 48
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 388.0 41
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 347.0 39
RA2159 Poly(I:C) 2
ug/mL
 2
M-CSF
 346.0 31
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
M-CSF
 545.0 35
N2645 Poly(I:C) 2
ug/mL
 2
M-CSF
 667.0 39