Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Poly(I:C) 2
ug/mL
 3
SCF
 48.5 56
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 48.0 81
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 43.0 50
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 41.5 72
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 27.5 88
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 49.5 54
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 47.0 80
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 41.0 67
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 48.0 58
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 45.0 44
RA1869 IL-1 alpha 100
ng/mL
 3
SCF
 36.0 77
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 46.0 72
N2759 IL-1 alpha 100
ng/mL
 3
SCF
 47.5 70
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 52.0 45
RA1931 IL-1 alpha 100
ng/mL
 3
SCF
 59.0 55
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 53.5 42
N2586 IL-1 alpha 100
ng/mL
 3
SCF
 52.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 38.5 48
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 42.5 68
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 32.0 80
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 36.0 65
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 36.0 57
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 42.0 54
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 35.0 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 40.5 70