Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Poly(I:C) 2
ug/mL
 4
IL3
 32.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 94.0 44
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 85.0 45
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 81.5 36
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 88.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 73.5 50
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 82.0 41
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 78.0 61
RA2159 IL-1 alpha 100
ng/mL
 4
IL3
 83.5 52
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 94.0 25
N2645 IL-1 alpha 100
ng/mL
 4
IL3
 80.0 36
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL3
 82.0 50
RA2708 IL-1 alpha 100
ng/mL
 4
IL3
 74.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL3
 52.0 35
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL3
 53.5 40
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL3
 41.0 54
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL3
 47.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL3
 53.0 48
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL3
 47.0 47
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL3
 38.0 42
RA2159 TNF-a 100
ng/mL
 4
IL3
 50.0 43
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL3
 45.0 45
N2645 TNF-a 100
ng/mL
 4
IL3
 52.5 38
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL3
 46.0 43
RA2708 TNF-a 100
ng/mL
 4
IL3
 55.0 50