Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 32.0 69
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 37.5 50
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 25.0 61
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 34.0 47
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 20.0 81
RA1869 Poly(I:C) 2
ug/mL
 3
HGF
 20.0 55
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 34.0 49
N2759 Poly(I:C) 2
ug/mL
 3
HGF
 31.0 57
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 27.0 53
RA1931 Poly(I:C) 2
ug/mL
 3
HGF
 30.0 51
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
HGF
 24.0 61
N2586 Poly(I:C) 2
ug/mL
 3
HGF
 31.0 57
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 65.0 67
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 45.5 58
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 76.0 53
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 42.0 77
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 46.0 80
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 53.0 63
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 48.0 72
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 44.0 75
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 45.0 57
RA1869 IL-1 alpha 100
ng/mL
 3
HGF
 39.0 59
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 64.5 60
N2759 IL-1 alpha 100
ng/mL
 3
HGF
 67.5 58
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
HGF
 56.0 58