Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 102.0 57
RA2159 IL-1 alpha 100
ng/mL
 4
IL-1RA
 93.0 59
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 55.0 45
N2645 IL-1 alpha 100
ng/mL
 4
IL-1RA
 62.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-1RA
 99.0 52
RA2708 IL-1 alpha 100
ng/mL
 4
IL-1RA
 103.0 65
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 149.0 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 149.0 61
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 121.0 58
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 131.0 55
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 132.0 57
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 127.0 50
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 142.5 56
RA2159 TNF-a 100
ng/mL
 4
IL-1RA
 165.5 64
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 139.5 46
N2645 TNF-a 100
ng/mL
 4
IL-1RA
 145.5 44
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-1RA
 158.5 52
RA2708 TNF-a 100
ng/mL
 4
IL-1RA
 152.0 44
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 29.0 53
RA2159 IKK16 2.0
uM
 4
IL-1RA
 29.0 51
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 26.0 49
N2645 IKK16 2.0
uM
 4
IL-1RA
 24.0 36
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-1RA
 26.0 67
RA2708 IKK16 2.0
uM
 4
IL-1RA
 31.0 51
RA2159 Tofacitinib 0.3
uM
 4
IL-1RA
 25.0 66