Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 49.0 53
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 29.5 70
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 42.0 77
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 39.5 74
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 51.0 67
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 47.0 65
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 37.5 62
RA1869 IL-1 alpha 100
ng/mL
 3
IL18
 23.0 61
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 52.0 49
N2759 IL-1 alpha 100
ng/mL
 3
IL18
 50.5 68
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 44.5 36
RA1931 IL-1 alpha 100
ng/mL
 3
IL18
 38.0 54
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL18
 44.0 47
N2586 IL-1 alpha 100
ng/mL
 3
IL18
 48.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 19.0 60
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 22.0 51
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 17.0 69
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 18.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 19.5 70
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 22.0 59
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL18
 15.0 76
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL18
 21.5 58
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 18.5 60
RA1869 TNF-a 100
ng/mL
 3
IL18
 19.0 57
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL18
 23.0 74