Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 63.0 65
N2759 Poly(I:C) 2
ug/mL
 3
IL-1RA
 63.0 75
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 62.0 59
RA1931 Poly(I:C) 2
ug/mL
 3
IL-1RA
 78.0 61
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-1RA
 86.0 62
N2586 Poly(I:C) 2
ug/mL
 3
IL-1RA
 77.0 65
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 22.0 68
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 32.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 20.0 73
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 37.0 69
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 24.0 66
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 31.0 69
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 20.0 63
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 43.0 56
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 70.0 79
RA1869 IL-1 alpha 100
ng/mL
 3
IL-1RA
 80.0 68
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 88.5 72
N2759 IL-1 alpha 100
ng/mL
 3
IL-1RA
 103.0 55
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 100.0 61
RA1931 IL-1 alpha 100
ng/mL
 3
IL-1RA
 80.5 68
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-1RA
 99.0 61
N2586 IL-1 alpha 100
ng/mL
 3
IL-1RA
 95.0 61
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 116.0 50
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 135.0 61
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1RA
 73.0 66