Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 97.0 55
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 99.5 58
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 98.5 66
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 114.0 46
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 96.0 47
RA2159 IL-1 alpha 100
ng/mL
 2
TNFb
 85.0 55
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 94.5 44
N2645 IL-1 alpha 100
ng/mL
 2
TNFb
 101.0 54
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
TNFb
 107.5 54
RA2708 IL-1 alpha 100
ng/mL
 2
TNFb
 97.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 43.0 47
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 34.0 54
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 39.0 67
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 34.5 66
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 41.0 74
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 38.5 62
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 36.0 64
RA2159 Poly(I:C) 2
ug/mL
 2
TNFb
 38.0 33
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 34.0 44
N2645 Poly(I:C) 2
ug/mL
 2
TNFb
 31.0 49
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
TNFb
 38.0 49
RA2708 Poly(I:C) 2
ug/mL
 2
TNFb
 36.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 43.0 47
RA2159 IKK16 2.0
uM
 2
TNFb
 41.0 55
N2645 5z-7-oxozeaenol 0.6
uM
 2
TNFb
 43.0 51