Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
LIF
 42.5 36
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
LIF
 44.0 45
RA1869 Poly(I:C) 2
ug/mL
 3
LIF
 40.0 51
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
LIF
 38.0 45
N2759 Poly(I:C) 2
ug/mL
 3
LIF
 43.0 50
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
LIF
 39.0 37
RA1931 Poly(I:C) 2
ug/mL
 3
LIF
 46.5 38
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
LIF
 52.0 35
N2586 Poly(I:C) 2
ug/mL
 3
LIF
 51.0 34
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 108.5 44
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 140.0 59
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 120.0 43
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 70.0 49
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 109.0 54
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 114.5 50
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 121.0 48
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 138.0 50
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 190.0 41
RA1869 IL-1 alpha 100
ng/mL
 3
LIF
 152.0 49
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 186.0 35
N2759 IL-1 alpha 100
ng/mL
 3
LIF
 188.0 34
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 200.0 34
RA1931 IL-1 alpha 100
ng/mL
 3
LIF
 192.5 54
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
LIF
 198.0 35
N2586 IL-1 alpha 100
ng/mL
 3
LIF
 221.0 43