Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 145.0 61
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 150.5 34
RA2159 TNF-a 100
ng/mL
 2
IL-1RA
 162.0 47
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 137.0 43
N2645 TNF-a 100
ng/mL
 2
IL-1RA
 128.0 65
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-1RA
 149.0 64
RA2708 TNF-a 100
ng/mL
 2
IL-1RA
 149.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 23.0 59
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 30.5 76
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 22.0 61
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 30.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 22.0 51
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 31.0 58
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 87.0 65
RA2159 IL-1 alpha 100
ng/mL
 2
IL-1RA
 91.0 71
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 58.0 55
N2645 IL-1 alpha 100
ng/mL
 2
IL-1RA
 74.0 58
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-1RA
 97.5 58
RA2708 IL-1 alpha 100
ng/mL
 2
IL-1RA
 101.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 23.0 58
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 28.0 79
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 22.0 64
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 24.0 54
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 24.0 57
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1RA
 25.0 68