Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 22.0 69
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 22.0 72
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 23.0 71
RA2159 Poly(I:C) 2
ug/mL
 4
MCP3
 32.0 69
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 19.5 56
N2645 Poly(I:C) 2
ug/mL
 4
MCP3
 34.0 67
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MCP3
 26.0 61
RA2708 Poly(I:C) 2
ug/mL
 4
MCP3
 26.5 52
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 27.0 71
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 27.0 70
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 25.0 69
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 26.0 75
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 24.0 79
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 29.0 69
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 84.0 65
RA2159 IL-1 alpha 100
ng/mL
 4
MCP3
 79.0 80
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 43.0 57
N2645 IL-1 alpha 100
ng/mL
 4
MCP3
 48.0 58
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
MCP3
 108.5 50
RA2708 IL-1 alpha 100
ng/mL
 4
MCP3
 117.5 56
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 19.0 65
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MCP3
 20.0 77
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 19.0 68
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
MCP3
 20.5 64
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
MCP3
 17.0 85