Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 69.0 53
N2759 Poly(I:C) 2
ug/mL
 3
MIG
 59.0 59
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 24.0 61
RA1931 Poly(I:C) 2
ug/mL
 3
MIG
 22.5 42
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MIG
 46.0 57
N2586 Poly(I:C) 2
ug/mL
 3
MIG
 57.0 55
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 29.0 82
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 27.0 82
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 59.0 83
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 57.5 98
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 25.0 75
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 25.0 91
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 40.0 76
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 58.0 73
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 31.5 64
RA1869 IL-1 alpha 100
ng/mL
 3
MIG
 19.0 80
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 111.0 63
N2759 IL-1 alpha 100
ng/mL
 3
MIG
 90.0 61
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 41.0 51
RA1931 IL-1 alpha 100
ng/mL
 3
MIG
 41.0 59
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MIG
 94.5 52
N2586 IL-1 alpha 100
ng/mL
 3
MIG
 88.0 65
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 21.0 67
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MIG
 24.0 64
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MIG
 33.0 85