Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MIG
 130.0 69
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 68.0 81
RA2159 TNF-a 100
ng/mL
 2
MIG
 50.0 63
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 93.0 51
N2645 TNF-a 100
ng/mL
 2
MIG
 98.5 72
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MIG
 176.0 35
RA2708 TNF-a 100
ng/mL
 2
MIG
 151.5 58
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 38.0 61
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 34.0 62
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 38.5 66
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 46.5 58
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 41.5 64
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 54.5 40
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 53.5 56
RA2159 IL-1 alpha 100
ng/mL
 2
MIG
 47.0 54
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 93.0 37
N2645 IL-1 alpha 100
ng/mL
 2
MIG
 89.5 52
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
MIG
 89.5 66
RA2708 IL-1 alpha 100
ng/mL
 2
MIG
 73.0 53
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 24.5 68
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 22.0 56
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 21.0 63
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 21.0 75
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 25.0 58
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
MIG
 35.0 83