Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 PH-797804 0.6
uM
 3
IL-17
 28.0 57
N2586 JNK-IN-8 3.0
uM
 3
IL-17
 28.0 67
N2586 PH-797804 0.6
uM
 3
IL-17
 32.0 51
0
IL-17
 70.0 33
0
IL-17
 68.0 47
0
IL-17
 67.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 66.0 70
RA2159 IKK16 2.0
uM
 4
IL-17
 63.0 51
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 64.0 69
N2645 IKK16 2.0
uM
 4
IL-17
 62.0 69
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-17
 65.0 65
RA2708 IKK16 2.0
uM
 4
IL-17
 69.5 56
RA2159 Tofacitinib 0.3
uM
 4
IL-17
 69.0 59
RA2159 4
IL-17
 60.0 49
N2645 Tofacitinib 0.3
uM
 4
IL-17
 62.0 48
N2645 4
IL-17
 66.5 72
RA2708 Tofacitinib 0.3
uM
 4
IL-17
 58.5 70
RA2708 4
IL-17
 61.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 71.0 48
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 92.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 68.0 77
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 58.0 64
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 65.0 63
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 63.0 60
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-17
 101.0 62