Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 71.0 | 61 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 69.0 | 62 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 72.5 | 54 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 78.0 | 53 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 48.0 | 49 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 56.5 | 44 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 70.0 | 45 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 22.5 | 54 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 109.0 | 45 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 93.5 | 56 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 93.0 | 43 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 65.0 | 43 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 125.0 | 48 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 109.0 | 57 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 54.0 | 59 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 69.0 | 51 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 52.5 | 64 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 72.5 | 46 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 60.0 | 35 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 88.0 | 49 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 96.0 | 51 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 60.0 | 51 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 56.0 | 41 | ||||
| RA1869 | 1 | IL-12 (p70) | 16.0 | 45 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 75.0 | 37 |