Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 13.0 94
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 14.0 74
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 24.0 72
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 23.0 58
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 17.0 75
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 17.0 77
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 12.0 68
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 16.0 63
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 13.5 68
RA1869 Poly(I:C) 2
ug/mL
 3
IL-7
 15.0 63
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 28.5 70
N2759 Poly(I:C) 2
ug/mL
 3
IL-7
 26.0 68
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 22.0 47
RA1931 Poly(I:C) 2
ug/mL
 3
IL-7
 25.0 69
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-7
 20.0 65
N2586 Poly(I:C) 2
ug/mL
 3
IL-7
 17.0 78
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 10.0 79
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 15.0 69
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 17.0 77
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 23.0 70
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.0 58
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.0 62
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.5 78
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 16.0 53
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-7
 19.0 78