Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IL-1 alpha 100
ng/mL
 4
IL-8
 13572.0 57
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-8
 239.5 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-8
 5267.5 64
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-8
 1347.5 70
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-8
 4199.0 69
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL-8
 392.5 62
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL-8
 8246.0 63
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-8
 11589.0 67
RA2159 TNF-a 100
ng/mL
 4
IL-8
 12159.0 50
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-8
 12330.0 49
N2645 TNF-a 100
ng/mL
 4
IL-8
 11835.0 63
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL-8
 12264.0 57
RA2708 TNF-a 100
ng/mL
 4
IL-8
 11167.5 44
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL-8
 114.0 62
RA2159 IKK16 2.0
uM
 4
IL-8
 125.0 65
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL-8
 131.5 64
N2645 IKK16 2.0
uM
 4
IL-8
 168.0 56
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL-8
 329.0 47
RA2708 IKK16 2.0
uM
 4
IL-8
 225.0 48
RA2159 Tofacitinib 0.3
uM
 4
IL-8
 134.5 60
RA2159 4
IL-8
 144.5 58
N2645 Tofacitinib 0.3
uM
 4
IL-8
 198.0 47
N2645 4
IL-8
 226.5 70
RA2708 Tofacitinib 0.3
uM
 4
IL-8
 329.0 54
RA2708 4
IL-8
 257.0 49