Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Poly(I:C) 2
ug/mL
 3
IL-8
 9770.0 67
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 115.0 80
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 2236.0 82
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 181.0 87
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 7312.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 137.0 71
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 2895.0 56
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 99.0 70
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 4462.5 56
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 12887.0 63
RA1869 IL-1 alpha 100
ng/mL
 3
IL-8
 12682.0 60
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 11758.0 57
N2759 IL-1 alpha 100
ng/mL
 3
IL-8
 13448.5 62
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 12866.0 59
RA1931 IL-1 alpha 100
ng/mL
 3
IL-8
 12184.0 80
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-8
 12777.0 68
N2586 IL-1 alpha 100
ng/mL
 3
IL-8
 12600.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-8
 183.5 64
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-8
 3927.0 62
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-8
 253.0 67
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-8
 5659.5 78
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-8
 578.5 60
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-8
 2500.5 70
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-8
 200.0 67
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-8
 5979.5 66