Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8617.0 | 62 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7640.0 | 69 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8161.5 | 50 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8257.0 | 55 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 613.0 | 70 | |
| RA1869 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 3040.0 | 57 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 388.5 | 50 | |
| N2759 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1715.0 | 50 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 1239.0 | 63 | |
| RA1931 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 2160.5 | 50 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 873.5 | 50 | |
| N2586 | IKK16 | 2.0 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 4162.5 | 64 | |
| RA1869 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8880.5 | 66 | |
| RA1869 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 9011.5 | 48 | ||||
| N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7710.0 | 66 | |
| N2759 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7830.0 | 55 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7193.0 | 69 | |
| RA1931 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 6306.0 | 63 | ||||
| N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 8109.5 | 54 | |
| N2586 | TNF-a | 100 | ng/mL | 3 | MCP-1 (MCAF) | 7746.0 | 49 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 56.5 | 66 | ||||
| RA1869 | IKK16 | 2.0 | uM | 3 | MCP-1 (MCAF) | 68.5 | 50 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 185.5 | 62 | ||||
| N2759 | IKK16 | 2.0 | uM | 3 | MCP-1 (MCAF) | 151.0 | 54 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 3 | MCP-1 (MCAF) | 77.0 | 69 |