Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| RA1869 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8317.0 | 35 | ||||
| N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7432.0 | 31 | |
| N2759 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7618.0 | 43 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 7300.0 | 29 | |
| RA1931 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 6720.5 | 40 | ||||
| N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8308.0 | 39 | |
| N2586 | IL-1 alpha | 100 | ng/mL | 1 | MCP-1 (MCAF) | 8141.0 | 41 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 48.0 | 61 | |
| RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 142.0 | 61 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 151.0 | 51 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 594.0 | 66 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 232.5 | 50 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 692.0 | 46 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 719.0 | 59 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 642.0 | 49 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 3587.0 | 45 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 310.0 | 49 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 4916.0 | 29 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 5823.0 | 44 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 4693.0 | 50 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 554.5 | 36 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 8026.0 | 47 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | MCP-1 (MCAF) | 7730.5 | 48 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | MCP-1 (MCAF) | 59.0 | 53 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | MCP-1 (MCAF) | 52.5 | 56 |