Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 17.0 89
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 25.0 73
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 15.0 75
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 28.0 77
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 17.0 81
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 22.0 57
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 19.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 31.0 75
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 65.0 54
RA1869 IL-1 alpha 100
ng/mL
 3
IL-4
 75.0 75
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 71.5 56
N2759 IL-1 alpha 100
ng/mL
 3
IL-4
 90.0 75
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 80.0 55
RA1931 IL-1 alpha 100
ng/mL
 3
IL-4
 69.0 66
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-4
 78.0 73
N2586 IL-1 alpha 100
ng/mL
 3
IL-4
 73.5 66
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-4
 78.0 63
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-4
 90.0 75
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-4
 55.5 82
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-4
 81.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-4
 85.0 60
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-4
 85.0 77
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-4
 67.0 66
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-4
 96.0 93
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-4
 108.0 65