Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 15.0 89
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 14.0 82
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 15.5 78
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 15.5 72
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 15.0 61
RA1869 Poly(I:C) 2
ug/mL
 3
IL-13
 17.5 72
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 20.0 77
N2759 Poly(I:C) 2
ug/mL
 3
IL-13
 18.0 65
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 16.0 67
RA1931 Poly(I:C) 2
ug/mL
 3
IL-13
 21.0 52
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-13
 22.5 56
N2586 Poly(I:C) 2
ug/mL
 3
IL-13
 21.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 13.0 83
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 16.0 79
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 12.5 82
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 18.0 61
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 15.0 76
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 15.0 69
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 17.0 58
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 18.0 69
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 16.0 78
RA1869 IL-1 alpha 100
ng/mL
 3
IL-13
 21.0 61
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 23.0 73
N2759 IL-1 alpha 100
ng/mL
 3
IL-13
 24.0 56
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-13
 23.0 73